With a $50 million donation to Children’s Hospital of Philadelphia and Penn Medicine on Tuesday, Philadelphia Eagles owner Jeffrey Lurie announced the creation of the Lurie Autism Institute in Philadelphia.

“This first-of-its kind Institute aims to be a global hub for autism research that connects scientists, clinicians, families, students, and donors,” per an Eagles press release.

According to the release, Lurie’s single donation is the largest toward autism research made to U.S. hospitals.

The Lurie family has supported autism research going back to 1977, when Lurie’s mother founded the Nancy Lurie Marks Family Foundation. That foundation led to the establishment of the The Lurie Center for Autism at Massachusetts General Hospital in Boston in 2009.

In 2018, Jeffrey Lurie started the Eagles Autism Foundation, which has raised more than $40 million, including over $10 million in 2025.